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PSI-Sigma: a comprehensive splicing-detection method for short-read and long-read RNA-seq analysis

MOTIVATION: Percent Spliced-In (PSI) values are commonly used to report alternative pre-mRNA splicing (AS) changes. Previous PSI-detection tools were limited to specific AS events and were evaluated by in silico RNA-seq data. We developed PSI-Sigma, which uses a new PSI index, and we employed actual...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Lin, Kuan-Ting, Krainer, Adrian R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901072/
https://ncbi.nlm.nih.gov/pubmed/31135034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz438
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