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SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements

Motivation: The inference of pre-mutation immunoglobulin (Ig) rearrangements is essential in the study of the antibody repertoires produced in response to infection, in B-cell neoplasms and in autoimmune disease. Often, there are several rearrangements that are nearly equivalent as candidates for a...

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Autores principales: Munshaw, Supriya, Kepler, Thomas B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844993/
https://ncbi.nlm.nih.gov/pubmed/20147303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq056
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