Modulation of intracellular Ca(2+) signalling in HeLa cells by the apoptotic cell death enhancer PK11195

1-(2-Chlorophenyl-N-methylpropyl)-3-isoquinolinecarboxamide (PK11195) is a proven enhancer of apoptotic cell death in a variety of cellular models. This effect is independent of its established cellular target, the mitochondrial benzodiazepine receptor (mBzR), since it is able to promote cell death...

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Hlavní autoři: Campanella, Michelangelo, Szabadkai, Gyorgy, Rizzuto, Rosario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844953/
https://ncbi.nlm.nih.gov/pubmed/18929543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.09.034
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