Role of the N- and C-terminal Domains in Binding of Apolipoprotein E Isoforms to Heparan Sulfate and Dermatan Sulfate: A Surface Plasmon Resonance Study

The ability of apolipoprotein E (apoE) to bind to cell-surface glycosaminoglycans (GAG) is important for lipoprotein remnant catabolism. Using surface plasmon resonance, we previously showed that the binding of apoE to heparin is a two-step process; the initial binding involves fast electrostatic in...

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Autori principali: Yamauchi, Yuko, Deguchi, Noriko, Takagi, Chika, Tanaka, Masafumi, Dhanasekaran, Padmaja, Nakano, Minoru, Handa, Tetsurou, Phillips, Michael C., Lund-Katz, Sissel, Saito, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844924/
https://ncbi.nlm.nih.gov/pubmed/18507396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8003999
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