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Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages.

The therapeutic efficacies of liposome-encapsulated ofloxacin and clarithromycin against Mycobacterium avium-M. intracellulare (MAI) were evaluated in a model of intramacrophage infection. Liposome encapsulation was found to markedly enhance the uptake of each of the drugs by human macrophages. The...

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Bibliographische Detailangaben
Hauptverfasser: Onyeji, C O, Nightingale, C H, Nicolau, D P, Quintiliani, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC284492/
https://ncbi.nlm.nih.gov/pubmed/8203849
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