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Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages.

The therapeutic efficacies of liposome-encapsulated ofloxacin and clarithromycin against Mycobacterium avium-M. intracellulare (MAI) were evaluated in a model of intramacrophage infection. Liposome encapsulation was found to markedly enhance the uptake of each of the drugs by human macrophages. The...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Onyeji, C O, Nightingale, C H, Nicolau, D P, Quintiliani, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8203849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.3.523
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