Recurrence of Type 1 Diabetes After Simultaneous Pancreas-Kidney Transplantation, Despite Immunosuppression, Is Associated With Autoantibodies and Pathogenic Autoreactive CD4 T-Cells

OBJECTIVE: To investigate if recurrent autoimmunity explained hyperglycemia and C-peptide loss in three immunosuppressed simultaneous pancreas-kidney (SPK) transplant recipients. RESEARCH DESIGN AND METHODS: We monitored autoantibodies and autoreactive T-cells (using tetramers) and performed biopsy....

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Xehetasun bibliografikoak
Egile Nagusiak: Vendrame, Francesco, Pileggi, Antonello, Laughlin, Elsa, Allende, Gloria, Martin-Pagola, Ainhoa, Molano, R. Damaris, Diamantopoulos, Stavros, Standifer, Nathan, Geubtner, Kelly, Falk, Ben A., Ichii, Hirohito, Takahashi, Hidenori, Snowhite, Isaac, Chen, Zhibin, Mendez, Armando, Chen, Linda, Sageshima, Junichiro, Ruiz, Phillip, Ciancio, Gaetano, Ricordi, Camillo, Reijonen, Helena, Nepom, Gerald T., Burke, George W., Pugliese, Alberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2010
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844842/
https://ncbi.nlm.nih.gov/pubmed/20086230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0498
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