Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis

OBJECTIVE: Hypothalamic leptin resistance is found in most common forms of obesity, such as diet-induced obesity, and is associated with increased expression of suppressor of cytokine signaling 3 (Socs3) in the hypothalamus of diet-induced obese animals. This study aims to determine the functional c...

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Bibliografiske detaljer
Main Authors: Reed, Alison S., Unger, Elizabeth K., Olofsson, Louise E., Piper, Merisa L., Myers, Martin G., Xu, Allison W.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844837/
https://ncbi.nlm.nih.gov/pubmed/20068134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1024
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