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Electrostatic Redesign of the [Myoglobin, Cytochrome b(5)] Interface to Create a Well-Defined Docked Complex with Rapid Inter-Protein Electron Transfer

[Image: see text] Cyt b(5) is the electron-carrier ‘repair’ protein that reduces met-Mb and met-Hb to their O(2)-carrying ferroheme forms. Studies of electron transfer (ET) between Mb and cyt b(5) revealed that they react on a “Dynamic Docking” (DD) energy landscape on which binding and reactivity a...

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Main Authors: Xiong, Peng, Nocek, Judith M., Griffin, Amanda K. K., Wang, Jingyun, Hoffman, Brian M.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844781/
https://ncbi.nlm.nih.gov/pubmed/19419145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902131d
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