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Evolving the [Myoglobin, Cytochrome b(5)] Complex from Dynamic Toward Simple Docking: Charging the Electron-Transfer Reactive Patch
We describe photo-initiated electron transfer (ET) from a suite of Zn-substituted myoglobin (1Mb) variants to cytochrome b(5) (b(5)). An electrostatic interface redesign strategy has led to the introduction of positive charges in the vicinity of the heme edge through D/E → K charge-reversal mutation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549022/ https://ncbi.nlm.nih.gov/pubmed/23067206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301134f |
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