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Single-particle reconstruction of biological macromolecules in electron microscopy – 30 years

This essay gives the author’s personal account on the development of concepts underlying single-particle reconstruction, a technique in electron microscopy of macromolecular assemblies with a remarkable record of achievements as of late. The ribosome proved to be an ideal testing ground for the deve...

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Autor principal: Frank, Joachim
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844734/
https://ncbi.nlm.nih.gov/pubmed/20025794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583509990059
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