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Molecular basis of thrombomodulin activation of slow thrombin

BACKGROUND: Coagulation is a highly regulated process where the ability to prevent blood loss after injury is balanced against the maintenance of blood fluidity. Thrombin is at the center of this balancing act. It is the critical enzyme for producing and stabilizing a clot, but when complexed with t...

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Main Authors: ADAMS, T.E., LI, W., HUNTINGTON, J.A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844540/
https://ncbi.nlm.nih.gov/pubmed/19656282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03563.x
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