Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin

Glycerotoxin (GLTx), a large neurotoxin isolated from the venom of the sea worm Glycera convoluta, promotes a long-lasting increase in spontaneous neurotransmitter release at the peripheral and central synapses by selective activation of Ca(v)2.2 channels. We found that GLTx stimulates the very high...

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Autori principali: Meunier, Frederic A., Nguyen, Tam H., Colasante, Cesare, Luo, Fujun, Sullivan, Robert K. P., Lavidis, Nickolas A., Molgó, Jordi, Meriney, Stephen D., Schiavo, Giampietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844322/
https://ncbi.nlm.nih.gov/pubmed/20215402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.049296
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