Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance.

We report on the identification of mutations associated with streptomycin resistance in Mycobacterium tuberculosis. Two isolates (3656 and 3976) showed a wild-type ribosomal protein, S12, but exhibited a single point mutation at 16S rRNA position 491 (C-->T) or 512 (C-->T), respectively. Sequence an...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Meier, A, Kirschner, P, Bange, F C, Vogel, U, Böttger, E C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8192448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.2.228
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