Elevated Expression of Paneth Cell CRS4C in Ileitis-prone SAMP1/YitFc Mice: REGIONAL DISTRIBUTION, SUBCELLULAR LOCALIZATION, AND MECHANISM OF ACTION

Paneth cells at the base of small intestinal crypts of Lieberkühn secrete host defense peptides and proteins, including α-defensins, as mediators of innate immunity. Mouse Paneth cells also express α-defensin-related Defcr-rs genes that code for cysteine-rich sequence 4C (CRS4C) peptides that have a...

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Bibliographische Detailangaben
Hauptverfasser: Shanahan, Michael T., Vidrich, Alda, Shirafuji, Yoshinori, Dubois, Claire L., Henschen-Edman, Agnes, Hagen, Susan J., Cohn, Steven M., Ouellette, André J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844197/
https://ncbi.nlm.nih.gov/pubmed/20056603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083220
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