NAD(+)-dependent Deacetylase SIRT3 Regulates Mitochondrial Protein Synthesis by Deacetylation of the Ribosomal Protein MRPL10

A member of the sirtuin family of NAD(+)-dependent deacetylases, SIRT3, is located in mammalian mitochondria and is important for regulation of mitochondrial metabolism, cell survival, and longevity. In this study, MRPL10 (mitochondrial ribosomal protein L10) was identified as the major acetylated p...

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Detalhes bibliográficos
Main Authors: Yang, Yongjie, Cimen, Huseyin, Han, Min-Joon, Shi, Tong, Deng, Jian-Hong, Koc, Hasan, Palacios, Orsolya M., Montier, Laura, Bai, Yidong, Tong, Qiang, Koc, Emine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844190/
https://ncbi.nlm.nih.gov/pubmed/20042612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053421
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