Apoptotic Death of Hematopoietic Tumor Cells through Potentiated and Sustained Adhesion to Fibronectin via VLA-4

It has been postulated that inactivated β1-integrins are involved in the disordered growth of hematopoietic tumor cells. We recently found that TNIIIA2, a peptide derived from tenascin-C, strongly activates β1-integrins through binding with syndecan-4. We show here that Ramos Burkitt's lymphoma...

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Bibliografiske detaljer
Main Authors: Saito, Yohei, Owaki, Toshiyuki, Matsunaga, Takuya, Saze, Mizue, Miura, Shogo, Maeda, Mao, Eguchi, Mayu, Tanaka, Rika, Taira, Junichi, Kodama, Hiroaki, Goto, Sumio, Niitsu, Yoshiroh, Terada, Hiroshi, Fukai, Fumio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844150/
https://ncbi.nlm.nih.gov/pubmed/20007695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027581
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