Tenascin-C-derived Peptide TNIIIA2 Highly Enhances Cell Survival and Platelet-derived Growth Factor (PDGF)-dependent Cell Proliferation through Potentiated and Sustained Activation of Integrin α5β1

Tenascin-C is an adhesion modulatory matrix protein that is highly expressed in tumors; however, its biochemical activity involved in tumorigenesis is not fully understood. On the other hand, increasing evidence indicates the importance of integrin α5β1 in cancer development. We previously demonstra...

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Detalhes bibliográficos
Main Authors: Tanaka, Rika, Seki, Yutaka, Saito, Yohei, Kamiya, Sadahiro, Fujita, Motomichi, Okutsu, Hiroaki, Iyoda, Takuya, Takai, Tatsuya, Owaki, Toshiyuki, Yajima, Hirofumi, Taira, Junichi, Hayashi, Ryo, Kodama, Hiroaki, Matsunaga, Takuya, Fukai, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067204/
https://ncbi.nlm.nih.gov/pubmed/24808173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546622
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