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Gating of the Mitochondrial Permeability Transition Pore by Long Chain Fatty Acyl Analogs in Vivo

The role played by long chain fatty acids (LCFA) in promoting energy expenditure is confounded by their dual function as substrates for oxidation and as putative classic uncouplers of mitochondrial oxidative phosphorylation. LCFA analogs of the MEDICA (MEthyl-substituted DICarboxylic Acids) series a...

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Detalhes bibliográficos
Main Authors: Samovski, Dmitri, Kalderon, Bella, Yehuda-Shnaidman, Einav, Bar-Tana, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844138/
https://ncbi.nlm.nih.gov/pubmed/20037159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080416
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