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Analysis of the Contribution of Charge Transport in Iodine-125 induced DNA Damage

Auger electron emitters, like iodine-125, are the radionuclides of choice for gene-targeted radiotherapy. The highly localized damage they induced in DNA is produced by three mechanisms: direct damage by the emitted Auger electrons, indirect damage by diffusible free radicals produced by Auger elect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ndlebe, Thabisile, Panyutin, Igor, Neumann, Ronald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844084/
https://ncbi.nlm.nih.gov/pubmed/20041764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1865.1
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