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Targeting the translational machinery as a novel treatment strategy for hematologic malignancies
The dysregulation of protein synthesis evident in the transformed phenotype has opened up a burgeoning field of research in cancer biology. Translation initiation has recently been shown to be a common downstream target of signal transduction pathways deregulated in cancer and initiated by mutated/o...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844014/ https://ncbi.nlm.nih.gov/pubmed/20075156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-220020 |
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