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Targeting the translational machinery as a novel treatment strategy for hematologic malignancies

The dysregulation of protein synthesis evident in the transformed phenotype has opened up a burgeoning field of research in cancer biology. Translation initiation has recently been shown to be a common downstream target of signal transduction pathways deregulated in cancer and initiated by mutated/o...

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Detalhes bibliográficos
Main Authors: Hagner, Patrick R., Schneider, Abraham, Gartenhaus, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844014/
https://ncbi.nlm.nih.gov/pubmed/20075156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-220020
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