JAK3/STAT5/6 Pathway Alterations Are Associated with Immune Deviation in CD8(+) T Cells in Renal Cell Carcinoma Patients

To investigate the molecular mechanisms underlying altered T cell response in renal cell carcinoma (RCC) patients, we compared autologous and allogeneic CD8(+) T cell responses against RCC line from RCC patients and their HLA-matched donors, using mixed lymphocyte/tumor cell cultures (MLTCs). In add...

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Detalhes bibliográficos
Main Authors: Cavalcanti, Elisabetta, Gigante, Margherita, Mancini, Vito, Battaglia, Michele, Ditonno, Pasquale, Capobianco, Carmela, Cincione, Raffaele I., Selvaggi, Francesco P., Herr, Wolfgang, Storkus, Walter J., Gesualdo, Loreto, Ranieri, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843943/
https://ncbi.nlm.nih.gov/pubmed/20339477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/935764
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