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Stable-isotope dilution LC–MS for quantitative biomarker analysis

The ability to conduct validated analyses of biomarkers is critically important in order to establish the sensitivity and selectivity of the biomarker in identifying a particular disease. The use of stable-isotope dilution (SID) methodology in combination with LC–MS/MS provides the highest possible...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ciccimaro, Eugene, Blair, Ian A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843934/
https://ncbi.nlm.nih.gov/pubmed/20352077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio.09.185
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