Liposomal Doxorubicin Increases Radiofrequency Ablation–induced Tumor Destruction by Increasing Cellular Oxidative and Nitrative Stress and Accelerating Apoptotic Pathways(1)

PURPOSE: To determine if oxidative and nitrative stress and/or apoptosis contribute to increased coagulation when combining radiofrequency (RF) ablation with liposomal doxorubicin. MATERIALS AND METHODS: Animal care committee approval was obtained. R3230 mammary adenocarcinomas in Fischer rats were...

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Autors principals: Solazzo, Stephanie A., Ahmed, Muneeb, Schor-Bardach, Rachel, Yang, Wei, Girnun, Geoffrey D., Rahmanuddin, Syed, Levchenko, Tatyana, Signoretti, Sabina, Spitz, Douglas R., Torchilin, Vladimir, Goldberg, S. Nahum
Format: Artigo
Idioma:Inglês
Publicat: Radiological Society of North America, Inc. 2010
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843831/
https://ncbi.nlm.nih.gov/pubmed/20160000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1148/radiol.09091196
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