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Radiofrequency Ablation–Induced Upregulation of Hypoxia-Inducible Factor-1α Can Be Suppressed with Adjuvant Bortezomib or Liposomal Chemotherapy
PURPOSE: To characterize upregulation of hypoxia-inducible factor (HIF)-1α after radiofrequency (RF) ablation and the influence of an adjuvant HIF-1α inhibitor (bortezomib) and nanodrugs on modulating RF ablation–upregulated hypoxic pathways. MATERIALS AND METHODS: Fisher 344 rats (n = 68) were used...
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| Foilsithe in: | J Vasc Interv Radiol |
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| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269608/ https://ncbi.nlm.nih.gov/pubmed/25439675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvir.2014.08.025 |
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