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Sindbis viral vector induced apoptosis requires translational inhibition and signaling through Mcl-1 and Bak
BACKGROUND: Sindbis viral vectors are able to efficiently target and kill tumor cells in vivo, as shown using pancreatic and ovarian cancer models. Infection results in apoptosis both in vitro and in vivo. Sindbis vector uptake is mediated by the LAMR, which is upregulated on a number of different t...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843653/ https://ncbi.nlm.nih.gov/pubmed/20152035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-37 |
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