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A tale of tails: sialidase is key to success in a model of phage therapy against K1-capsulated Escherichia coli
Prior studies treating mice infected with Escherichia coli O18:K1:H7 observed that phages requiring the K1 capsule for infection (K1-dep) were superior to capsule-independent (K1-ind) phages. We show that three K1-ind phages all have low fitness when grown on cells in serum whereas fitnesses of four...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843586/ https://ncbi.nlm.nih.gov/pubmed/20006993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.11.040 |
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