RECOGNITION OF FUNGAL PROTEASE ACTIVITIES INDUCES CELLULAR ACTIVATION AND EOSINOPHIL-DERIVED NEUROTOXIN RELEASE IN HUMAN EOSINOPHILS

Eosinophils are multifunctional leukocytes implicated in the pathogenesis of asthma and in immunity to certain organisms. Associations between exposure to an environmental fungus, such as Alternaria, and asthma have been recognized clinically. Protease-activated receptors (PARs) are G protein-couple...

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Main Authors: Matsuwaki, Yoshinori, Wada, Kota, White, Thomas A., Benson, Linda M., Charlesworth, M. Cristine, Checkel, James L., Inoue, Yoshinari, Hotta, Kyoko, Ponikau, Jens U, Lawrence, Christopher B., Kita, Hirohito
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843542/
https://ncbi.nlm.nih.gov/pubmed/19864598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901220
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