Pimecrolimus Reduces Eosinophil Activation Associated with Calcium Mobilization

BACKGROUND: Pimecrolimus is a calcineurin inhibitor that inhibits T cell and mast cell activation and effectively treats atopic dermatitis. However, its effects on eosinophils, a cell type implicated in allergic disease pathology, are unknown. Therefore, we examined the effects of pimecrolimus on eo...

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Main Authors: Plager, Douglas A., Henke, Susan A., Matsuwaki, Yoshinori, Madaan, Arvind, Squillace, Diane L., Dierkhising, Ross A., Kita, Hirohito
格式: Artigo
語言:Inglês
出版: S. Karger AG 2009
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Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718564/
https://ncbi.nlm.nih.gov/pubmed/19127068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000189194
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