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Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections.

Oral doses of 400 mg of lomefloxacin were administered once daily prior to breakfast to 10 middle-aged to elderly hospitalized patients with chronic obstructive pulmonary disease during treatment for bronchopulmonary infections. Serial plasma and sputum samples and fractional urine samples were obta...

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Detalhes bibliográficos
Main Authors: Kovarik, J M, Hoepelman, A I, Smit, J M, Sips, P A, Rozenberg-Arska, M, Glerum, J H, Verhoef, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC284353/
https://ncbi.nlm.nih.gov/pubmed/1336948
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