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Pharmacokinetics and inflammatory fluid penetration of sparfloxacin.

A single 400-mg oral dose of sparfloxacin was given to each of six healthy male volunteers, and the concentrations of the drug were measured in plasma, cantharides-induced inflammatory fluid, and urine over the subsequent 52 h. The mean peak concentration in plasma of 1.6 micrograms/ml was attained...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Johnson, J H, Cooper, M A, Andrews, J M, Wise, R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2444
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