Pharmacokinetics and inflammatory fluid penetration of sparfloxacin.

A single 400-mg oral dose of sparfloxacin was given to each of six healthy male volunteers, and the concentrations of the drug were measured in plasma, cantharides-induced inflammatory fluid, and urine over the subsequent 52 h. The mean peak concentration in plasma of 1.6 micrograms/ml was attained...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Johnson, J H, Cooper, M A, Andrews, J M, Wise, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336947/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2444
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