Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys.

2',3'-Dideoxy-5-fluoro-3'-thiacytidine (FTC) is a nucleoside analog that selectively inhibits human immunodeficiency and hepatitis B viruses in vitro. In this study, the preclinical pharmacokinetics of racemic FTC in rhesus monkeys following intravenous and oral administration were characterized. Th...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Schinazi, R F, Boudinot, F D, Ibrahim, S S, Manning, C, McClure, H M, Liotta, D C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1992
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284348/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336946/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2432
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