Therapeutic Potential of Proteasome Inhibition in Duchenne and Becker Muscular Dystrophies

Duchenne muscular dystrophy (DMD) and its milder allelic variant, Becker muscular dystrophy (BMD), result from mutations of the dystrophin gene and lead to progressive muscle deterioration. Enhanced activation of proteasomal degradation underlies critical steps in the pathogenesis of the DMD/BMD dys...

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Main Authors: Gazzerro, Elisabetta, Assereto, Stefania, Bonetto, Andrea, Sotgia, Federica, Scarfì, Sonia, Pistorio, Angela, Bonuccelli, Gloria, Cilli, Michele, Bruno, Claudio, Zara, Federico, Lisanti, Michael P., Minetti, Carlo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2010
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Regular Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843476/
https://ncbi.nlm.nih.gov/pubmed/20304949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090468
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