Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection.

The prophylactic and therapeutic properties of 3'-azido-3'-deoxythymidine (AZT) against simian immunodeficiency virus (SIV) infection were tested in four 3-month-old rhesus macaques. The infant monkeys were inoculated intravenously with a low dose (1 to 10 100% animal infectious doses) of...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Van Rompay, K K, Marthas, M L, Ramos, R A, Mandell, C P, McGowan, E K, Joye, S M, Pedersen, N C
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1489181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.11.2381
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