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A V(H)H That Neutralizes the Zinc Metalloproteinase Activity of Botulinum Neurotoxin Type A
The current treatment of botulism is to administer animal-derived antitoxin, which frequently causes severe adverse reactions in the recipients. In this study, a heavy chain antibody fragment (VH/V(H)H) phage display library was constructed by amplification of the immunoglobulin genes of a nonimmune...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843216/ https://ncbi.nlm.nih.gov/pubmed/20093370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.073163 |
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