FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation

Dandy-Walker malformation (DWM), the most common human cerebellar malformation, has only one characterized associated locus1,2. Here we characterize a second DWM-linked locus on 6p25.3, showing that deletions or duplications encompassing FOXC1 are associated with cerebellar and posterior fossa malfo...

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Autori principali: Aldinger, Kimberly A, Lehmann, Ordan J, Hudgins, Louanne, Chizhikov, Victor V, Bassuk, Alexander G, Ades, Lesley C, Krantz, Ian D, Dobyns, William B, Millen, Kathleen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843139/
https://ncbi.nlm.nih.gov/pubmed/19668217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.422
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