Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis

Heterozygous deletions encompassing the ZIC1;ZIC4 locus have been identified in a subset of individuals with the common cerebellar birth defect Dandy-Walker malformation (DWM). Deletion of Zic1 and Zic4 in mice produces both cerebellar size and foliation defects similar to human DWM, confirming a re...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Blank, Marissa C., Grinberg, Inessa, Aryee, Emmanuel, Laliberte, Christine, Chizhikov, Victor V., Henkelman, R. Mark, Millen, Kathleen J.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042874/
https://ncbi.nlm.nih.gov/pubmed/21307096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker