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MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

The matrix metalloproteinase MMP-9/gelatinase B is upregulated in angiogenic dysplasias and invasive cancers of the epidermis in a mouse model of multistage tumorigenesis elicited by HPV16 oncogenes. Transgenic mice lacking MMP-9 show reduced keratinocyte hyperproliferation at all neoplastic stages...

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Bibliografiska uppgifter
Huvudupphovsmän: Coussens, Lisa M., Tinkle, Christopher L., Hanahan, Douglas, Werb, Zena
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843102/
https://ncbi.nlm.nih.gov/pubmed/11081634
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