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Calpain as a therapeutic target in traumatic brain injury

The family of calcium-activated neutral proteases, calpains, appears to play a key role in neuropathologic events following traumatic brain injury (TBI). Neuronal calpain activation has been observed within minutes to hours after either contusive or diffuse brain trauma in animals, suggesting that c...

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Bibliografski detalji
Glavni autori: Saatman, Kathryn E., Creed, Jennifer, Raghupathi, Ramesh
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842949/
https://ncbi.nlm.nih.gov/pubmed/20129495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.11.002
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