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Molecular population genetics of PCSK9: a signature of recent positive selection

OBJECTIVE: Proprotein convertase subtilisin-like kexin type 9 (PCSK9) is a newly discovered serine protease that plays a key role in regulating plasma low-density lipoprotein (LDL) cholesterol levels. Both rare mutations and common variants in the coding regions of PCSK9 affect LDL cholesterol level...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ding, Keyue, Kullo, Iftikhar J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842919/
https://ncbi.nlm.nih.gov/pubmed/18300938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f44d99
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