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Molecular population genetics of PCSK9: a signature of recent positive selection
OBJECTIVE: Proprotein convertase subtilisin-like kexin type 9 (PCSK9) is a newly discovered serine protease that plays a key role in regulating plasma low-density lipoprotein (LDL) cholesterol levels. Both rare mutations and common variants in the coding regions of PCSK9 affect LDL cholesterol level...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842919/ https://ncbi.nlm.nih.gov/pubmed/18300938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f44d99 |
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