Secreted Semaphorins Control Spine Distribution and Morphogenesis in the Postnatal CNS

The majority of excitatory synapses in the mammalian CNS are formed on dendritic spines1, and spine morphology and distribution are critical for synaptic transmission2–6, synaptic integration and plasticity7. Here, we show that a secreted semaphorin, Sema3F, is a negative regulator of spine developm...

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Bibliografiske detaljer
Main Authors: Tran, Tracy S., Rubio, Maria E., Clem, Roger L., Johnson, Dontais, Case, Lauren, Tessier-Lavigne, Marc, Huganir, Richard L., Ginty, David D., Kolodkin, Alex L.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842559/
https://ncbi.nlm.nih.gov/pubmed/20010807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08628
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