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Tissue factor in antiphospholipid antibody-induced pregnancy loss: a pro-inflammatory molecule

Fetal loss in patients with antiphospholipid antibodies (aPL) has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically complement activation with generation of the anaphylotoxin C5a, is an essential mediator of fetal injury. We have analysed the ro...

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Bibliographic Details
Main Authors: Girardi, G, Mackman, N
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842117/
https://ncbi.nlm.nih.gov/pubmed/18827058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203308094994
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