Positive allosteric modulators of the human sweet taste receptor enhance sweet taste

To identify molecules that could enhance sweetness perception, we undertook the screening of a compound library using a cell-based assay for the human sweet taste receptor and a panel of selected sweeteners. In one of these screens we found a hit, SE-1, which significantly enhanced the activity of s...

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Библиографические подробности
Главные авторы: Servant, Guy, Tachdjian, Catherine, Tang, Xiao-Qing, Werner, Sara, Zhang, Feng, Li, Xiaodong, Kamdar, Poonit, Petrovic, Goran, Ditschun, Tanya, Java, Antoniette, Brust, Paul, Brune, Nicole, DuBois, Grant E., Zoller, Mark, Karanewsky, Donald S.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842059/
https://ncbi.nlm.nih.gov/pubmed/20173092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911670107
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