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Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling

Biodegradable scaffolds seeded with bone marrow mononuclear cells (BMCs) are the earliest tissue-engineered vascular grafts (TEVGs) to be used clinically. These TEVGs transform into living blood vessels in vivo, with an endothelial cell (EC) lining invested by smooth muscle cells (SMCs); however, th...

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Main Authors: Roh, Jason D., Sawh-Martinez, Rajendra, Brennan, Matthew P., Jay, Steven M., Devine, Lesley, Rao, Deepak A., Yi, Tai, Mirensky, Tamar L., Nalbandian, Ani, Udelsman, Brooks, Hibino, Narutoshi, Shinoka, Toshiharu, Saltzman, W. Mark, Snyder, Edward, Kyriakides, Themis R., Pober, Jordan S., Breuer, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842056/
https://ncbi.nlm.nih.gov/pubmed/20207947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911465107
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