Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling

Biodegradable scaffolds seeded with bone marrow mononuclear cells (BMCs) are the earliest tissue-engineered vascular grafts (TEVGs) to be used clinically. These TEVGs transform into living blood vessels in vivo, with an endothelial cell (EC) lining invested by smooth muscle cells (SMCs); however, th...

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Autori principali: Roh, Jason D., Sawh-Martinez, Rajendra, Brennan, Matthew P., Jay, Steven M., Devine, Lesley, Rao, Deepak A., Yi, Tai, Mirensky, Tamar L., Nalbandian, Ani, Udelsman, Brooks, Hibino, Narutoshi, Shinoka, Toshiharu, Saltzman, W. Mark, Snyder, Edward, Kyriakides, Themis R., Pober, Jordan S., Breuer, Christopher K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842056/
https://ncbi.nlm.nih.gov/pubmed/20207947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911465107
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