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Critical role of IRF-5 in regulation of B-cell differentiation

IFN-regulatory factor 5 (IRF-5), a member of the IRF family, is a transcription factor that has a key role in the induction of the antiviral and inflammatory response. When compared with C57BL/6 mice, Irf5(−/−) mice show higher susceptibility to viral infection and decreased serum levels of type I I...

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Detalhes bibliográficos
Main Authors: Lien, Chunyang, Fang, Chee-Mun, Huso, David, Livak, Ferenc, Lu, Runqing, Pitha, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842054/
https://ncbi.nlm.nih.gov/pubmed/20176957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911193107
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