Imiquimod enhances IFN-γ production and effector function of T cells infiltrating human squamous cell carcinomas of the skin

Squamous cell carcinomas (SCC) are sun-induced skin cancers that are particularly numerous and aggressive in patients taking T cell immunosuppressant medications. Imiquimod is a topical immune response modifier and TLR7 agonist that induces the immunologic destruction of SCC and other skin cancers....

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Detalhes bibliográficos
Main Authors: Huang, Susan J., Hijnen, Dirkjan, Murphy, George F., Kupper, Thomas S., Calarese, Adam W., Mollet, Ilse G., Schanbacher, Carl F., Miller, Danielle M., Schmults, Chrysalyne, Clark, Rachael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841955/
https://ncbi.nlm.nih.gov/pubmed/19516264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2009.151
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